Patterns of Use of e-Cigarettes and Their Respiratory Effects: A Critical Umbrella Review
- 09algor
- Mar 10
- 1 min read
11 March 2025
Giusy Rita Maria La Rosa https://orcid.org/0000-0001-5127-5299 g_larosa92@live.it, Riccardo Polosa, and Renée O'Leary
Conclusion
Five systematic reviews rated at AMSTAR2 high and moderate confidence found no significant change in respiratory function with EC use, either with dual use with continued cigarette use, exclusive use after quitting smoking, or naïve use by consumers who have never smoked. The null findings can be attributed to the weaknesses of acute studies, by the smoking history of the participants masking potential changes in test results, and by the inclusion of participants with very little exposure to EC due to a low frequency of vaping. Our assessment of the methodological and reporting quality of 12 systematic reviews found that the majority were subpar, further reducing our confidence in the literature. For accuracy, future studies must conduct their analyses on the specific patterns and frequency of EC use. Choices of testing methods should be carefully evaluated for their appropriateness and accuracy. Based on the current research, there is insufficient evidence of any significant change in the short or medium term in respiratory function with any pattern of EC use.